Oral systemic acne treatments help to improve moderate-severe acne.

These include various anti-inflammatory antibiotics and the combined oral contraceptive pill.

They are often used as combination treatments with topical therapies to achieve maximum efficacy.

These treatments again take 2-3 months before significant improvement is seen.

If after 4 months of treatment significant improvement is not achieved, you may require isotretinoin treatment prescribed by a dermatologist.